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Invitrogen
RUFY1 Polyclonal Antibody
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RUFY1 Antibody (PA5-117107) in WB
Western blot analysis of RUFY1 in extracts of various cell lines. Samples were incubated with RUFY1 Polyclonal antibody (Product # PA5-117107) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-117107
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 439-708 of human RUFY1 (NP_0794343)
偶联物
形式
Liquid
浓度
2.78 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Mouse kidney, Mouse heart, Rat lung
Immunogen sequence: EKDTHEKQDT LVALRQQLEE VKAINLQMFH KAQNAESSLQ QKNEAITSFE GKTNQVMSSM KQMEERLQHS ERARQGAEER SHKLQQELGG RIGALQLQLS QLHEQCSSLE KELKSEKEQR QALQRELQHE KDTSSLLRME LQQVEGLKKE LRELQDEKAE LQKICEEQEQ ALQEMGLHLS QSKLKMEDIK EVNQALKGHA WLKDDEATHC RQCEKEFSIS RRKHHCRNCG HIFCNTCSSN ELALPSYPKP VRVCDSCHTL LLQRCSSTAS
靶标信息
This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FYVE-finger containing protein; Rab4-interacting protein; Rab4a interacting protein; RUN and FYVE domain-containing protein 1
基因别名: 3000002E04Rik; Rabip4; Rufy1; ZFYVE12
UniProt ID: (Mouse) Q8BKQ4
Entrez Gene ID: (Mouse) 216724, (Rat) 360521
