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Alomone Labs, LTD
RXFP2 (extracellular) Polyclonal Antibody
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RXFP2 (extracellular) Antibody (ARR-012-200UL) in WB
Western blot analysis of rat brain (lanes 1 and 5), rat testis (lanes 2 and 6), mouse brain (lanes 3 and 7) and mouse testis (lanes 4 and 8): - 1-4. Anti-RXFP2 (extracellular) Antibody (#ARR-012), (1:400).5-8. Anti-RXFP2 (extracellular) Antibody , preincubated with RXFP2 (extracellular) Blocking Peptide (#BLP-RR012).
产品信息
ARR-012-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CFPLHYDQAEDFGSR, corresponding to amino acid residues 556-570 of mouse RXFP2, 2nd extracellular loop
偶联物
形式
Lyophilized
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
The activity of this relaxin receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP and may also be a receptor for Leydig insulin-like peptide. Expressed in embryonic and adult gonads of males and females, as well in male gubernarculum and in brain. Not detected in kidney, spleen and heart.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein coupled receptor affecting testicular descent; G protein-coupled receptor 106; G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; INSL3 receptor; leucine-rich repeat-containing G protein-coupled receptor 8; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2; Relaxin receptor 2
基因别名: Gpcr; Gpr106; Great; Lgr8; Rxfp2
UniProt ID: (Mouse) Q91ZZ5
Entrez Gene ID: (Mouse) 140498, (Rat) 363866
oocyte maturation
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of cell proliferation
male gonad development
positive regulation of cAMP biosynthetic process
negative regulation of apoptotic process
