Invitrogen

Reelin Recombinant Rabbit Monoclonal Antibody (K01_3U15)

查看其他13个Reelin抗体

问题与答案

问题与答案

问题与答案

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抗体检测数据 (1)

Reelin Antibody in Western Blot (WB)

Reelin Antibody in Western Blot (WB)

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Reelin Antibody (MA567000) in WB

Western Blot analysis of Reelin in HepG2 lysates using Reelin Recombinant Monoclonal Antibody (Product # MA567000).

Reelin Antibody in Western Blot (WB)

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Reelin Antibody in Western Blot (WB) — Western Blot analysis of Reelin in HepG2 lysates using Reelin Recombinant Monoclonal Antibody (Product # MA567000).

产品信息

MA567000

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

产品规格

种属反应

Human, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293F

分类

Recombinant Monoclonal

类型

Antibody

克隆号

K01_3U15

抗原

A synthesized peptide derived from human Reelin.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 0.05% BSA, 50% glycerol, 150mM NaCl

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Reelin in an extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Reelin; unnamed protein product

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基因别名: ETL7; LIS2; PRO1598; Reelen; reeler; RELN; RL

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UniProt ID: (Human) P78509, (Rat) P58751

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Entrez Gene ID: (Human) 5649, (Rat) 24718

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peptidase activity serine-type peptidase activity hydrolase activity metal ion binding receptor agonist activity lipoprotein particle receptor binding very-low-density lipoprotein particle receptor binding molecular_function protein serine/threonine/tyrosine kinase activity extracellular matrix glycoprotein extracellular matrix protein

cell morphogenesis neuron migration proteolysis cell adhesion axon guidance central nervous system development brain development learning long-term memory locomotory behavior associative learning glial cell differentiation regulation of gene expression positive regulation of neuron projection development dendrite development cell migration spinal cord patterning ventral spinal cord development hippocampus development cerebral cortex tangential migration layer formation in cerebral cortex cerebral cortex development forebrain development positive regulation of TOR signaling protein localization to synapse reelin-mediated signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process regulation of neuron differentiation response to pain regulation of behavior modulation of synaptic transmission positive regulation of small GTPase mediated signal transduction positive regulation of protein kinase B signaling positive regulation of synaptic transmission, glutamatergic regulation of synaptic activity long-term synaptic potentiation positive regulation of dendritic spine morphogenesis regulation of synapse maturation positive regulation of synapse maturation postsynaptic density assembly NMDA glutamate receptor clustering postsynaptic density protein 95 clustering receptor localization to synapse motor neuron migration lateral motor column neuron migration positive regulation of long-term synaptic potentiation positive regulation of lateral motor column neuron migration interneuron migration positive regulation of excitatory postsynaptic potential regulation of neuron migration cell morphogenesis involved in differentiation midgut development memory response to mechanical stimulus response to toxic substance response to hormone response to lithium ion positive regulation of phosphatidylinositol 3-kinase signaling response to organic cyclic compound response to insecticide peptidyl-tyrosine phosphorylation dentate gyrus development orbitofrontal cortex development hypothalamus development response to progesterone positive regulation of CREB transcription factor activity social behavior thyroid hormone metabolic process response to drug response to amino acid response to ethanol positive regulation of protein kinase activity response to axon injury positive regulation of peptidyl-tyrosine phosphorylation response to corticosterone response to electrical stimulus positive regulation of protein tyrosine kinase activity response to fatty acid cellular response to dexamethasone stimulus regulation of N-methyl-D-aspartate selective glutamate receptor activity positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity