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Invitrogen
Relaxin 3 Polyclonal Antibody
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产品信息
PA5-75701
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues in Human Relaxin 3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Relaxin 3 is part of the Relaxin-like peptide family that plays an important neuropeptide signaling role. Relaxin 3 is a ligand for two structurally related G protein-coupled receptors, human Relaxin receptor 3 and Relaxin receptor 4. The greatest levels of Relaxin 3 expression occur in the brain, specifically in the pons/medulla, with highest levels in the pars ventromedialis of the dorsal tegmental nucleus and with lower levels in the hippocampus and olfactory regions. Significant expression is also observed in the spleen, thymus, lung and ovary. Relaxin 3 inhibits Forskolin-stimulated cAMP accumulation in a dose-dependent manner in cells that express Relaxin receptor 3. Acute and repeated administration of Relaxin 3 causes a decrease in levels of the plasma thyroid stimulating hormone, suggesting that Relaxin 3 may play a role in long-term control of food intake.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: insulin-like 7; Insulin-like peptide 7; Insulin-like peptide INSL7; PRO20213; Prorelaxin H3; Prorelaxin M3; Relaxin-3; UNQ6188
基因别名: H3; INSL7; M3; RLN3; RXN3; UNQ6188/PRO20213; ZINS4
UniProt ID: (Human) Q8WXF3, (Mouse) Q8CHK2
Entrez Gene ID: (Human) 117579, (Mouse) 212108
