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Abnova
Rgr Polyclonal Antibody, MaxPab™
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产品信息
H00266747-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Rgr (AAI01110.1, 1 a.a. approximately 410 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPALEPAPPL LADLGPALEP ESPAALGPPG YLHSAPGPAP APGEGPPPGT VLEPQSAPES SCPCRGSVKN QPSEELPDMT TFPPRLLAEQ LTLMDAELFK KVVLYECLGC IWGQGHLKGN EHMAPTVRAT IAHFNRLTNC ITTSCLGDHS MRARDRARVV EHWIKVAREC LSLNNFSSVH VIVSALCSNP IGQLHKTWAG VSSKSMKELK ELCKKDTAVK RDLLIKAGSF KVATQERNPQ RAQMRLRRQK KGVVPFLGDF LTELQRLDSA IPDDLDGNTN KRSKEVRVLQ EMQLLQVAAM NYRLRPLEKF VTYFTRMEQL SDKERLHCSV TISVHCNVCL LGSSPSSASQ AAGTTAVHHH VRLFCCCCSA TSCPASWSPK TRRLATSCSG WEPTGMLART PALHHPSPRP
靶标信息
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RGR-opsin; RPE retinal G-protein coupled receptor; RPE-retinal G protein-coupled receptor
基因别名: RGR; RP44
UniProt ID: (Human) P47804
Entrez Gene ID: (Human) 5995
