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Invitrogen
Rhesus D antigen (Trinbelimab Biosimilar) Recombinant Human Monoclonal Antibody
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产品信息
MA562692
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1-lambda3
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.86 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The Rhesus D (RhD) antigen is one of the major antigens in the Rhesus blood group system, encoded by the RHD gene located on chromosome 1p36.11. Structurally, the RhD protein is a multi-pass transmembrane protein spanning the erythrocyte membrane, integrating a polypeptide of around 417 amino acids. RhD is highly immunogenic; its presence or absence on the surface of red blood cells determines the Rh-positive or Rh-negative status, respectively. The RhD antigen plays a role in maintaining the integrity of the red blood cell membrane. Functionally, the RhD antigen's primary clinical significance lies in its role in blood transfusion and in hemolytic disease of the fetus and newborn (HDFN), where an Rh-negative mother may develop antibodies against Rh-positive fetal red blood cells leading to potential complications.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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