Rho Monoclonal Antibody (4D2)

GTPase activity obsolete small monomeric GTPase activity protein binding GTP binding myosin binding GDP binding protein kinase binding protein domain specific binding Rho GDP-dissociation inhibitor binding profilin binding GBD domain binding

mitotic cytokinesis actin filament organization cell adhesion signal transduction small GTPase mediated signal transduction endosome to lysosome transport positive regulation of endothelial cell migration regulation of cell migration negative regulation of cell migration positive regulation of apoptotic process positive regulation of angiogenesis negative regulation of cell cycle endothelial tube morphogenesis cellular response to hydrogen peroxide cellular response to ionizing radiation regulation of modification of postsynaptic structure negative regulation of establishment of endothelial barrier cell migration positive regulation of cell migration positive regulation of protein complex assembly regulation of actin cytoskeleton organization apical junction assembly positive regulation of stress fiber assembly positive regulation of lipase activity meiotic spindle organization cell morphogenesis response to hypoxia kidney development angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure alpha-beta T cell lineage commitment regulation of systemic arterial blood pressure by endothelin aortic valve formation regulation of transcription from RNA polymerase II promoter cytoskeleton organization microtubule depolymerization cell-matrix adhesion Rho protein signal transduction skeletal muscle tissue development regulation of actin polymerization or depolymerization response to xenobiotic stimulus response to mechanical stimulus response to glucose negative regulation of cell-substrate adhesion regulation of neuron projection development negative regulation of neuron projection development cerebral cortex cell migration forebrain radial glial cell differentiation actin cytoskeleton organization cell differentiation positive regulation of cell growth androgen receptor signaling pathway positive regulation of actin filament polymerization establishment or maintenance of actin cytoskeleton polarity stress-activated protein kinase signaling cascade cytoplasmic microtubule organization positive regulation of cytokinesis negative regulation of intracellular steroid hormone receptor signaling pathway regulation of osteoblast proliferation cell junction assembly substrate adhesion-dependent cell spreading Roundabout signaling pathway cleavage furrow formation apolipoprotein A-I-mediated signaling pathway embryonic cleavage polar body extrusion after meiotic divisions odontogenesis positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling stress fiber assembly response to amino acid beta selection negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process endothelial cell migration ossification involved in bone maturation wound healing, spreading of cells establishment of epithelial cell apical/basal polarity response to ethanol negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of translation positive regulation of cell adhesion negative regulation of cell size positive regulation of vasoconstriction positive regulation of smooth muscle contraction GTP metabolic process positive regulation of alpha-beta T cell differentiation neuron projection morphogenesis regulation of dendrite development negative chemotaxis response to glucocorticoid spindle localization regulation of calcium ion transport negative regulation of synapse assembly bone trabecula morphogenesis regulation of microtubule cytoskeleton organization cellular response to lipopolysaccharide cellular response to cytokine stimulus cellular response to progesterone stimulus semaphorin-plexin signaling pathway positive regulation of podosome assembly positive regulation of protein serine/threonine kinase activity negative regulation of cell migration involved in sprouting angiogenesis mitotic spindle assembly negative regulation of oxidative phosphorylation endothelial tube lumen extension skeletal muscle satellite cell migration negative regulation of reactive oxygen species biosynthetic process mitotic cleavage furrow formation positive regulation of vascular smooth muscle contraction negative regulation of vascular smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration positive regulation of leukocyte adhesion to vascular endothelial cell regulation of modification of postsynaptic actin cytoskeleton cellular response to chemokine regulation of neural precursor cell proliferation positive regulation of T cell migration endocytosis insulin receptor signaling pathway regulation of cell shape establishment of cell polarity cortical actin cytoskeleton organization cellular response to insulin stimulus positive regulation of transcription from RNA polymerase II promoter positive regulation of glucose import positive regulation of filopodium assembly negative regulation of protein localization to plasma membrane