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Invitrogen
Ricin Recombinant Mouse Monoclonal Antibody (4G11)
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Ricin Antibody (MA566334) in SDS-PAGE
SDS-PAGE characterization of Ricin under reducing conditions. Lane M: Protein marker (kDa); Lane RC-C: Purified Ricin Recombinant Monoclonal (Product # MA566334). Ricin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-364.
产品信息
MA566334
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4G11
抗原
Ricin.
偶联物
形式
Liquid
浓度
6.9 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Ricin is a highly toxic protein derived from the seeds of the castor plant, Ricinus communis. It functions as a type II ribosome-inactivating protein, inhibiting protein synthesis and leading to cell death. Ricin is composed of two subunits: the enzymatic A chain (RTA) and the binding B chain (RTB), which facilitate its entry into cells. Due to its high toxicity, ricin has been studied extensively for its potential use as a bioweapon, and efforts have been made to develop neutralizing antibodies as antidotes. These antibodies target both ricin isoforms D and E, providing protection by binding to and neutralizing the toxin. The development of these antibodies is crucial for therapeutic interventions against ricin poisoning, which can occur through ingestion, inhalation, or injection.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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