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Invitrogen
Rosmantuzumab Humanized Recombinant Human Monoclonal Antibody
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Rosmantuzumab Humanized Antibody (MA5-42128) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human RSPO3 protein expressed in CHO cells using a Rosmantuzumab biosimilar monoclonal antibody (Product # MA5-42128). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
产品信息
MA5-42128
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human RSPO3
偶联物
形式
Liquid
浓度
1.72 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.5
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Rosmantuzumab is a biosimilar that targets RSPO3. RSPO3 is a member of the R-spondin family and plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. RSPO3 has been shown to be involved in regulating the balance between angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis and may be involved in tumor development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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