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Invitrogen
S100A8 Polyclonal Antibody
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S100A8 Antibody (PA5-120730) in IHC (P)
Immunohistochemistry analysis of S100A8 in paraffin-embedded mouse spleen. Samples were incubated with S100A8 Polyclonal antibody (Product # PA5-120730) using a dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-120730
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-89 of mouse S100A8 (NP_038678.1).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.879 mg/mL
规格
187.9 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: Mouse lung, Mouse spleen, Rat spleen.
Immunogen sequence: MPSELEKALS NLIDVYHNYS NIQGNHHALY KNDFKKMVTT ECPQFVQNIN IENLFRELDI NSDNAINFEE FLAMVIKVGV ASHKDSHKE
靶标信息
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calgranulin-A; chemotactic cytokine CP-10; chemotactic S100 protein; leukocyte L1 complex light chain; migration inhibitory factor-related protein 8; MRP-8; p8; pro-inflammatory S100 cytokine; S100 A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium-binding protein A8; unnamed protein product
基因别名: 60B8Ag; B8Ag; Caga; CFAg; CP-10; MRP8; p8
UniProt ID: (Mouse) P27005, (Rat) P50115
Entrez Gene ID: (Mouse) 20201, (Rat) 116547
leukocyte migration involved in inflammatory response
positive regulation of peptide secretion
autophagy
astrocyte development
peptidyl-cysteine S-nitrosylation
neutrophil chemotaxis
response to lipopolysaccharide
regulation of toll-like receptor signaling pathway
autocrine signaling
endothelial cell migration
positive regulation of inflammatory response
neutrophil aggregation
positive regulation of intrinsic apoptotic signaling pathway
chronic inflammatory response
response to zinc ion
response to ethanol
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