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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • S100B Antibodies

          NeoBiotechnologies

          S100B (Astrocyte and Melanoma Marker) Monoclonal Antibody (S100B/1012)

          查看其他71个S100B抗体

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          说明书
          实验方案
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          说明书
          实验方案
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          Cite S100B (Astrocyte and Melanoma Marker) Monoclonal Antibody (S100B/1012)

          • 抗体检测数据 (6)
          S100B (Astrocyte and Melanoma Marker) Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          S100B (Astrocyte and Melanoma Marker) Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          图: 1 / 6

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          S100B (Astrocyte and Melanoma Marker) Antibody (6285-MSM2-P1ABX) in ICC/IF

          Confocal Immunofluorescent analysis of A2058 cells using AF488-labeled Isotype Control Monoclonal Antibody (IgG2a) (Green). F-actin filaments were labeled with DyLight 554 Phalloidin (red). DAPI was used to stain the cell nuclei (blue). (Negative Control). {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

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          S100B (Astrocyte and Melanoma Marker) Antibody in Immunocytochemistry (ICC/IF)
          S100B (Astrocyte and Melanoma Marker) Antibody in Immunocytochemistry (ICC/IF)
          S100B (Astrocyte and Melanoma Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          S100B (Astrocyte and Melanoma Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          S100B (Astrocyte and Melanoma Marker) Antibody in Peptide array (ARRAY)
          S100B (Astrocyte and Melanoma Marker) Antibody in SDS-PAGE (SDS-PAGE)
          S100B (Astrocyte and Melanoma Marker) Monoclonal Antibody (S100B/1012)

          产品信息

          6285-MSM2-P1ABX

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1-2 µg/mL
          -

          免疫组化(石蜡) (IHC (P))

          Assay-dependent
          -

          免疫组织化学(多聚甲醛固定) (IHC (PFA))

          0.25-0.5 µg/mL
          -

          免疫细胞化学 (ICC/IF)

          1-2 µg/mL
          -

          流式细胞分析 (Flow)

          1-2 µg/10^6 cells
          -

          肽阵列 (Array)

          Assay-dependent
          -

          免疫电镜技术 (IM)

          Assay-dependent
          -
          产品规格

          种属反应

          Bovine, Human, Mouse, Rat

          宿主/亚型

          Mouse / IgG2a, kappa

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          S100B/1012

          抗原

          Recombinant full-length human S100B protein
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated
          • CF 488
          • Request custom conjugation

          形式

          Liquid

          浓度

          1 mg/mL

          纯化类型

          Protein A/G

          保存液

          PBS, pH 7.4

          内含物

          no preservative

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          靶标信息

          S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: Protein S100-B; S-100 calcium-binding protein, beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S100 calcium-binding protein, beta (neural); S100 protein beta chain; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural

          查看更多 收起

          基因别名: AI850290; Bpb; NEF; S100; S100-B; S100B; S100beta; S100P

          查看更多 收起

          UniProt ID: (Human) P04271, (Bovine) A4IFR6, (Mouse) P50114, (Rat) P04631

          查看更多 收起

          Entrez Gene ID: (Human) 6285, (Bovine) 525716, (Mouse) 20203, (Rat) 25742

          查看更多 收起

          功能
          calcium ion binding protein binding zinc ion binding identical protein binding protein homodimerization activity S100 protein binding tau protein binding calcium-dependent protein binding RAGE receptor binding kinase inhibitor activity receptor binding metal ion binding calmodulin-related
          参与通路
          axonogenesis central nervous system development learning or memory memory cell proliferation positive regulation of cell proliferation regulation of cell shape positive regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling innate immune response regulation of neuronal synaptic plasticity astrocyte differentiation response to glucocorticoid response to methylmercury long-term synaptic potentiation cellular response to hypoxia negative regulation of skeletal muscle cell differentiation regulation of translation phosphorylation negative regulation of kinase activity positive regulation of complement activation astrocyte activation negative regulation of monocyte chemotactic protein-1 production energy reserve metabolic process cellular calcium ion homeostasis regulation of cytokine biosynthetic process regulation of long-term neuronal synaptic plasticity positive regulation of synaptic transmission
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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