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The S1P gene, which may refer to the sphingosine-1-phosphate (S1P) signaling molecule rather than an actual gene, is central to numerous cellular processes. Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite. It is synthesized by the phosphorylation of sphingosine through the action of sphingosine kinases (SphK1 and SphK2). S1P functions as a ligand for a family of G-protein-coupled receptors, designated S1P1 through S1P5. Structurally, S1P is a simple molecule, but its signaling complexity is notable. Functionally, S1P regulates diverse biological processes, including cell proliferation, survival, migration, and angiogenesis. It is also involved in immune cell trafficking and vascular maturation. Aberrant S1P signaling has been implicated in various diseases, including cancer, fibrosis, and inflammatory conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。