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Antibody detects endogenous levels of total SAA1/2.
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SAA; SAA2; serum amyloid A 1; serum amyloid A 2; serum amyloid A protein; Serum amyloid A-1 protein; Serum amyloid A-2 protein; tumor protein p53 inducible protein 4
基因别名: AW111173; PIG4; SAA; Saa-1; Saa-2; SAA1; SAA2; TP53I4
UniProt ID: (Human) P0DJI8, (Human) P0DJI9, (Mouse) P05366, (Mouse) P05367
Entrez Gene ID: (Human) 6288, (Human) 6289, (Mouse) 20208, (Mouse) 20209
分子生物学功能: apolipoprotein