Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Abnova
SAA4 Monoclonal Antibody (3C11)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
H00006291-M08
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3C11
抗原
SAA4 (AAH07026, 1 a.a. approximately 130 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: MRLFTGIVFC SLVMGVTSES WRSFFKEALQ GVGDMGRAYW DIMISNHQNS NRYLYARGNY DAAQRGPGGV WAAKLISRSR VYLQGLIDYY LFGNSSTVLE DSKSNEKAEE WGRSGKDPDR FRPDGLPKKY
靶标信息
Serum Amyloid A4 (SAA4) is a gene that encodes one of the constitutively expressed serum amyloid proteins. Located on chromosome 11, SAA4 is part of the serum amyloid A (SAA) superfamily, which includes other highly homologous genes like SAA1, SAA2, and SAA3. Unlike its counterparts, SAA4 is not an acute-phase reactant but is persistently expressed across different tissues, including plasma, where it associates with high-density lipoprotein (HDL). SAA4 is involved in lipid metabolism and inflammatory responses, albeit not directly induced by inflammatory stimuli like other SAA proteins. It appears as multiple isoforms, some of which may be glycosylated. Recent studies have shown that SAA4 expression encompasses a broad spectrum of physiological conditions and may serve as a marker in diseases involving chronic inflammation and persistent pathological states such as neovascular age-related macular degeneration. The gene's constitutive expression pattern suggests its fundamental role in maintaining homeostasis rather than responding dynamically to acute inflammatory challenges.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: C-SAA; Constitutively expressed serum amyloid A protein; Serum amyloid A-4 protein
基因别名: C-SAA; CSAA; SAA4
UniProt ID: (Human) P35542
Entrez Gene ID: (Human) 6291
