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Invitrogen
SAMD8 Polyclonal Antibody
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产品信息
PA5-114138
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human SAMD8
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MQTYPPLPDI FLDSVPRIPW AFAMTEVCGM ILCYIWLLVL LLHKHRSILL
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
靶标信息
Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ceramide phosphoethanolamine synthase; CPE synthase; epididymis luminal protein 177; epididymis secretory sperm binding protein Li 181mP; FLJ25082; HEL-S-181mP; RP11-487I5.5; SAM domain-containing protein 8; SMSr; sphingomyelin synthase related; Sphingomyelin synthase-related protein 1; Sterile alpha motif domain-containing protein 8
基因别名: HEL-177; SAMD8; SMSr
UniProt ID: (Human) Q96LT4
Entrez Gene ID: (Human) 142891
