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Immunogen sequence: TDAFLKADDY IEITGAGGKK YRISTAIDDM EAYTKLTDNI FLEILYSTDP KLKDAREILK QIEYRNLFKY VGETQPTGQI KIKREDYESL PKEVASAKPK VLLDVKLKAE DFIVDVINMD YGMQEKNPID HVSFYCKTAP NRAIRITKNQ VSQLLPEKFA EQLIRVYCKK VDRKSLYAAR QYFVQWCADR NFTKPQDGDV IAPLITPQKK EWNDSTSVQN PTRLREASKS RVQLFKDDPM; Positive Samples: HepG2, HeLa, MCF-7, Mouse spleen; Cellular Location: Nucleus
This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DCIP; Dendritic cell-derived IFNG-induced protein; Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; hSAMHD1; IFN-gamma induced; Interferon-gamma-inducible protein Mg11; Monocyte protein 5; MOP-5; mSAMHD1; RP1-132F21.1; SAM domain and HD domain 1; SAM domain and HD domain-containing protein 1
基因别名: CHBL2; DCIP; E330031J07Rik; HDDC1; Mg11; Mg21; MOP-5; MOP5; SAMHD1; SBBI88
UniProt ID: (Human) Q9Y3Z3, (Mouse) Q60710
Entrez Gene ID: (Human) 25939, (Rat) 311580, (Mouse) 56045