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Invitrogen
SARS-CoV-2 ORF7b Recombinant Rabbit Monoclonal Antibody (HL1453)
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图: 1 / 3
SARS-CoV-2 ORF7b Antibody (MA5-47052) in ICC/IF
Immunocytochemistry analysis of SARS-CoV-2 ORF7b in paraffin-embedded mock and SARS-CoV-2 ORF7b transfected 293T cell pellet. Green: SARS-CoV-2 (COVID-19) ORF7b stained by SARS-CoV-2 (COVID-19) ORF7b monoclonal antibody (Product # MA5-47052) diluted at 1:1,000. Blue: Fluoroshield with DAPI. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-47052
应用
建议稀释比
已发表文章
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL1453
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) ORF7b. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
靶标信息
The accessory proteins of coronaviruses are essential for virus-host interactions and the modulation of host immune responses|It has been reported that accessory protein ORF3a encoded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can induce apoptosis, and accessory protein ORF6 and ORF8 could be inhibitors of the type-I interferon (IFN) signaling pathway|However, the function of accessory protein ORF7b is largely unknown|Recent studies have shown that ORF7b promoted expression of IFN-beta, TNF-alpha, and IL-6, activated type-I IFN signaling through IRF3 phosphorylation, and activated TNF alpha-induced apoptosis in HEK293T cells and Vero E6 cells [PMID: 34484133]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: COVID19 ORF7b
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