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Invitrogen
SARS-CoV-2 Spike Protein S1 NTD Recombinant Rabbit Monoclonal Antibody (235)
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产品信息
MA5-60385
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
235
抗原
Recombinant SARS-CoV-2 Spike S1 protein (Val16-Arg685).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recognize SARS-CoV-2 Spike S1-NTD. Doesn't recognize SARS-CoV-2 Spike RBD and S2. Has cross-reactivity with SARS-CoV.. Has cross-reactivity in ELISA and WB with: SARS-COV-2 Omicron (KP.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Spike S1+S2 ECD-His; SARS-CoV-2 Spike S1-His; SARS-CoV-2 Spike S1 NTD-Fc & AVI; SARS-CoV-2 Spike S1 NTD-His & AVI; SARS-CoV Spike S1+S2 ECD-His. Has cross-reactivity in ELISA with: SARS-CoV-2 (XEC) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB.1.16) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB.1.5) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB.1) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BF.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4.6) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2.75) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2.75.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (B.1.1.529) S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.1.1) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2) Spike S1 Protein; SARS-CoV-2 Omicron (BA.2) Spike S1 NTD Protein; SARS-CoV-2 XD(BA.1 x AY.4) Spike S1+S2 trimer Protein; SARS-CoV-2 Delta (B.1.617.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Delta (B.1.617.2) Spike S1 Protein; SARS-CoV-2 Delta (B.1.617.2) Spike S1 NTD Protein; SARS-CoV-2 Spike S1 NTD-Fc & AVI; Medium cross-reactivity in ELISA with: SARS-CoV-2 Omicron (BA.2.75) Spike RBD Protein; No cross-reactivity in ELISA and WB with: SARS-CoV-2 Spike RBD-His; SARS-CoV-2 Spike S2 ECD-His; MERS-CoV Spike S1+S2 ECD-His; HCoV-OC43 Spike S1+S2 ECD-His; HCoV-HKU1 (isolate N5) Spike S1+S2 ECD-His; HCoV-NL63 Spike S1+S2 ECD-His; HCoV-229E Spike S1+S2 ECD-His; No cross-reactivity in ELISA with: SARS-CoV-2 Omicron (XBB.1.5) Spike RBD Protein; SARS-CoV-2 Omicron (XBB) Spike RBD Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike RBD Protein; SARS-CoV-2 Omicron (BA.4.6/BF.7) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.75.2) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.3.20) Spike RBD Protein; SARS-CoV-2 Omicron (B.1.1.529) Spike RBD Protein; SARS-CoV-2 Omicron (BA.1.1) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.12.1) Spike RBD Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike RBD Protein; SARS-CoV-2 Omicron (BA.5) Spike RBD Protein; SARS-CoV-2 Delta (B.1.617.2) Spike RBD Protein
靶标信息
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain (Spike Protein). The Spike protein is the main surface antigen of the coronavirus. The glycosylated Spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. CoV diversity is reflected in the variable Spike proteins (S proteins), which have evolved into forms differing in their receptor interactions and their response to various environmental triggers of virus-cell membrane fusion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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