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Invitrogen
SCAP Polyclonal Antibody
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图: 1 / 7
SCAP Antibody (PA5-35341) in ICC/IF
Immunocytochemistry analysis of SCAP in HeLa cells. Samples were incubated with SCAP polyclonal antibody (Product # PA5-35341) using a dilution of 1:100 for 2 h at room temperature followed by Alexa Fluor® 488 conjugated donkey anti-rabbit at a dilution of 1:1,000 for 1hr. Cells were fixed with 4% PFA (20 min) and permeabilized with Triton X-100 (0.2%, 30 min). Nuclei were counterstained with Hoechst 33342 (blue) (10 µg/mL, 5 min).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-35341
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 604-632 amino acids from the central region of human SCAP
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.48 mg/mL
规格
192 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology.
靶标信息
The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KIAA0199; SCAP; scap {ECO:0000312|EMBL:AAI31853.1}; Sreb cleavage-activating protein; SREBP cleavage activating protein; SREBP cleavage-activating protein; Sterol regulatory element-binding protein cleavage-activating protein; unnamed protein product
基因别名: 9530044G19; KIAA0199; mKIAA0199; PSEC0227; SCAP
UniProt ID: (Human) Q12770, (Mouse) Q6GQT6, (Rat) A2RRU4
Entrez Gene ID: (Human) 22937, (Mouse) 235623, (Rat) 301024
response to hypoxia
lipid metabolic process
immune response
steroid metabolic process
cholesterol metabolic process
regulation of fatty acid metabolic process
response to insulin
SREBP signaling pathway
response to vitamin B3
regulation of fatty acid biosynthetic process
regulation of cholesterol biosynthetic process
negative regulation of cholesterol biosynthetic process
positive regulation of cholesterol biosynthetic process
cargo loading into COPII-coated vesicle
aging
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