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Invitrogen
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Immunogen sequence: PNSAPKAGLP GATGPMAVRP EEAVRGLGAG TESSRRAQEP VSGCGSPEQD PQKQAEEERQ EEPEYENVVP I
Highest antigen sequence indentity to the following orthologs: Mouse - 62%, Rat - 31%.
The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells and mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Transcription factors ZNF444/EZF-2 and SP1 are found to be responsible for the regulation of this gene. Five alternatively spliced transcript variants encoding distinct isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Acetyl LDL receptor; MGC47738; Scavenger receptor class F member 1; scavenger receptor class F, member 1; Scavenger receptor expressed by endothelial cells 1; SREC-I
基因别名: KIAA0149; SCARF1; SREC; SREC-I; SREC1
UniProt ID: (Human) Q14162
Entrez Gene ID: (Human) 8578