Abnova

SCIN Polyclonal Antibody, MaxPab™

Name: SCIN Polyclonal Antibody, MaxPab\u2122
Brand: Abnova
SKU: H00085477-D01P

查看其他11个SCIN抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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SCIN Antibody (H00085477-D01P) in WB

Western Blot analysis of SCIN expression in transfected 293T cell line by SCIN MaxPab polyclonal antibody. Lane 1: SCIN transfected lysate(52.80 KDa). Lane 2: Non-transfected lysate. .

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Immunogen image

Immunogen Image SCIN Polyclonal Antibody, MaxPab™

产品信息

H00085477-D01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

SCIN (NP_149119.1, 1 a.a. approximately 468 a.a) full-length human protein.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MAKLYMVSDA SGSMRVTVVA EENPFSMAML LSEECFILDH GAAKQIFVWK GKDANPQERK AAMKTAEEFL QQMNYSKNTQ IQVLPEGGET PIFKQFFKDW RDKDQSDGFG KVYVTEKVAQ IKQIPFDASK LHSSPQMAAQ HNMVDDGSGK VEIWRVENNG RIQVDQNSYG EFYGGDCYII LYTYPRGQII YTWQGANATR DELTTSAFLT VQLDRSLGGQ AVQIRVSQGK EPVHLLSLFK DKPLIIYKNG TSKKGGQAPA PPTRLFQVRR NLASITRIVE VDVDANSLNS NDVFVLKLPQ NSGYIWVGKG ASQEEEKGAE YVASVLKCKT LRIQEGEEPE EFWNSLGGKK DYQTSPLLET QAEDHPPRLY GCSNKTGRFV IEEIPGEFTQ DDLAEDDVML LDAWEQIFIW IGKDANEVEK KESLKSAKMY LETDPSGRDK RTPIVIIKQG HEPPTFTGWF LGWDSSKW

靶标信息

The SCIN gene, also known as scinderin, encodes for a calcium-dependent actin filament-severing protein that is involved in the regulation of the cytoskeleton. It plays a significant role in actin filament dynamics, influencing cellular processes such as cell shape, motility, secretion, and division. SCIN has been identified as a novel oncogene, with its abnormal expression strongly correlated to various cancers, including glioma and uterine corpus endometrial carcinoma. Specific mutations like S673F and S381Y in SCIN are linked with poor prognosis and are potential targets for cancer diagnosis, prognosis, and treatment strategies.

仅用于科研。不用于诊断过程。未经明确授权不得转售。