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Abnova
SCN3A Monoclonal Antibody (2F8)
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产品信息
H00006328-M06
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2F8
抗原
SCN3A (NP_008853, 1861 a.a. approximately 1960 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: LCESGEMDAL RIQMEDRFMA SNPSKVSYEP ITTTLKRKQE EVSAAIIQRN FRCYLLKQRL KNISSNYNKE AIKGRIDLPI KQDMIIDKLN GNSTPEKTDG
靶标信息
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BIII; brain III voltage-gated sodium channel; Sodium channel protein brain III subunit alpha; Sodium channel protein type 3 subunit alpha; Sodium channel protein type III subunit alpha; sodium channel, voltage gated, type III alpha subunit; sodium channel, voltage-gated, type III, alpha polypeptide; Voltage-gated sodium channel subtype III; Voltage-gated sodium channel subunit alpha Nav1.3
基因别名: KIAA1356; NAC3; Nav1.3; SCN3A
UniProt ID: (Human) Q9NY46
Entrez Gene ID: (Human) 6328
sodium ion transport
nervous system development
response to wounding
neuronal action potential
sensory perception of pain
regulation of ion transmembrane transport
sodium ion transmembrane transport
response to pyrethroid
regulation of postsynaptic membrane potential
cellular response to antibiotic
membrane depolarization during action potential
