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Recommended positive controls: A431, H1299, HeLa.
Predicted reactivity: Mouse (96%), Rat (94%), Xenopus laevis (83%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coated vesicle-associated kinase of 90 kDa; likely ortholog of mouse N-terminal kinase-like protein; N-terminal kinase-like protein; SCY1-like protein 1; SCY1-like, kinase-like 1; Telomerase regulation-associated protein; Telomerase transcriptional element-interacting factor; telomerase transcriptional elements-interacting factor; Teratoma-associated tyrosine kinase
基因别名: CVAK90; GKLP; HT019; NKTL; NTKL; P105; SCAR21; SCYL1; TAPK; TEIF; TRAP
UniProt ID: (Human) Q96KG9
Entrez Gene ID: (Human) 57410