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Bethyl Laboratories
SEC24B Polyclonal Antibody
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FIGURE: 1 / 2
SEC24B Antibody (A304-877A) in WB
Detection of human SEC24B by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SEC24B antibody (Product # A304-877A) (lot A304-877A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 10 seconds.
Product Details
A304-877A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 300 to 350 of Human Protein transport protein Sec24B.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24A may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein transport protein Sec24B; SEC24 related gene family, member B; SEC24-related protein B; secretory protein 24
Gene Aliases: SEC24; SEC24B
UniProt ID: (Human) O95487
Entrez Gene ID: (Human) 10427
neural tube closure
antigen processing and presentation of peptide antigen via MHC class I
outflow tract morphogenesis
intracellular protein transport
ER to Golgi vesicle-mediated transport
vesicle-mediated transport
antigen processing and presentation of exogenous peptide antigen via MHC class II
cochlear nucleus development
aorta morphogenesis
COPII vesicle coating
auditory receptor cell stereocilium organization
lung lobe morphogenesis
coronary artery morphogenesis
pulmonary artery morphogenesis
regulation of establishment of planar polarity involved in neural tube closure
regulation of cargo loading into COPII-coated vesicle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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