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Abnova
SEMA6A Monoclonal Antibody (1C8)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00057556-M05
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1C8
抗原
SEMA6A (NP_065847, 21 a.a. approximately 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: PEDSEPISIS HGNYTKQYPV FVGHKPGRNT TQRHRLDIQM IMIMNGTLYI AARDHIYTVD IDTSHTEEIY CSKKLTWKSR QADVDTCRMK GKHKDECHNF
靶标信息
SEMA6A can act as repulsive axon guidance cues. It may play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; sema VIa; SEMA6A-1; semaphorin 6A-1; semaphorin VIA; unnamed protein product
基因别名: HT018; SEMA; SEMA6A1; SEMAQ; VIA
UniProt ID: (Human) Q9H2E6
Entrez Gene ID: (Human) 57556
neural crest cell migration
apoptotic process
cytoskeleton organization
cell surface receptor signaling pathway
nervous system development
axon guidance
organ morphogenesis
negative regulation of angiogenesis
cellular response to vascular endothelial growth factor stimulus
negative chemotaxis
negative regulation of ERK1 and ERK2 cascade
semaphorin-plexin signaling pathway
negative regulation of cell adhesion involved in sprouting angiogenesis
negative regulation of vascular endothelial growth factor signaling pathway
negative regulation of sprouting angiogenesis
positive regulation of neuron migration
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