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Invitrogen
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Highest antigen sequence identity to the following orthologs: Mouse- 89%, Rat- 92%.
Sequence of this protein is as follows: GDLRTFGQSA NGQWRNSTPS SSSSLQKSRN SRSLYLETRK TSSGLSNSFA GKSNHHCHVS AYEKSFPIKP VPSPSWSGSC RRSLLSPKKT QRRHVSTAEE TVQEEEREIY RQLLQMVTGK
SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SEN1; Sentrin-specific protease 1; Sentrin/SUMO-specific protease SENP1
基因别名: SENP1
Entrez Gene ID: (Human) 29843