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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: KKQRKILWRK GIHLAFSEKW NTGFGGFKKF YFHQHLCILK AKLGRPVTWN RQLRHFQGRK KALQIQKTWI KDEHLCAKTK FNVATQNVST LSSKVKRKDA KHFISSSK
SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the "GG" region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp564O1016; FKSG45; FLJ42398; MGC27076; sentrin/SUMO-specific protease SENP5; SUMO1/sentrin specific peptidase 5; SUMO1/sentrin specific protease 5; unnamed protein product
UniProt ID: (Human) Q96HI0
Entrez Gene ID: (Human) 205564