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Abnova
SERPINA3 Monoclonal Antibody (1C10)
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产品信息
H00000012-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1C10
抗原
SERPINA3 (AAH03559, 25 a.a. approximately 423 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: PNSPLDEENL TQENQDRGTH VDLGLASANV DFAFSLYKQL VLKAPDKNVI FSPLSISTAL AFLSLGAHNT TLTEILKGLK FNLTETSEAE IHQSFQHLLR TLNQSSDELQ LSMGNAMFVK EQLSLLDRFT EDAKRLYGSE AFATDFQDSA AAKKLINDYV KNGTRGKITD LIKDLDSQTM MVLVNYIFFK AKWEMPFDPQ DTHQSRFYLS KKKWVMVPMM SLHHLTIPYF RDEELSCTVV ELKYTGNASA LFILPDQDKM EEVEAMLLPE TLKRWRDSLE FREIGELYLP KFSISRDYNL NDILLQLGIE EAFTSKADLS GITGARNLAV SQVVHKAVLD VFEEGTEASA ATAVKITLLS ALVETRTIVR FNRPFLMIIV PTDTQNIFFM SKVTNPKQA
靶标信息
SERPINA encodes Alpha 1-ACT. It is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ACT; Alpha-1-antichymotrypsin; Cell growth-inhibiting gene 24/25 protein; Growth inhibiting protein 24; Growth inhibiting protein 25; growth-inhibiting protein 24; growth-inhibiting protein 25; MGC88254; Serine (or cysteine) proteinase inhibitor clade A member 3; serine (or cysteine) proteinase inhibitor, clade A, member 3; Serpin A3; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
基因别名: AACT; ACT; GIG24; GIG25; SERPINA3
UniProt ID: (Human) P01011
Entrez Gene ID: (Human) 12
