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In Western blots, approximately 10% cross-reactivity with recombinant human (rh) Serpin B8, rhSerpin B9, and rhSerpin B6 is observed and less than 1% cross-reactivity with rhSerpin A1, D1, E2, I2, recombinant mouse Serpin A1, C1, E1, F1, and F2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
The superfamily of high molecular weight serine proteinase inhibitors. A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: serine (or cysteine) peptdiase inhibitor, clade B, member 8; serine (or cysteine) proteinase inhibitor, clade B, member 8; serine protease inhibitor 8; Serpin B8
基因别名: CAP-2; CAP2; NK10; ovalbumin; Serpinb8; Spi8
UniProt ID: (Mouse) O08800
Entrez Gene ID: (Mouse) 20725