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PA1-43065 detects SERPINC1 in mouse samples.
PA1-43065 has successfully been used in Western blot and ELISA applications. Predicted molecular weight of approximately 150 kDa.
PA1-43065 was derived from mouse antithrombin.
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: anti-thrombin 3; Antithrombin; Antithrombin 3; Antithrombin-III; ATIII; MGC22579; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; Serpin C1; serpin peptidase inhibitor, clade C, member 1
基因别名: AI114908; At-3; At3; ATIII; Serpinc1
UniProt ID: (Mouse) P32261
Entrez Gene ID: (Mouse) 11905