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Invitrogen
SERPINE2 Monoclonal Antibody (244404)
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产品信息
MA5-61111
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
244404
抗原
Mouse myeloma cell line NS0-derived recombinant mouse Serpin E2/PN1, Ser20-Pro397
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GDN; Glia derived nexin; Glia-derived nexin; P17; Peptidase inhibitor 7; PI-7; PN-1; Protease nexin 1; Protease nexin I; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serine (or cysteine) proteinase inhibitor, clade E, member 2; serine protease inhibitor 4; Serine protease-inhibitor 4; Serpin E2; SERPINE 2
基因别名: B230326M24Rik; PAI-1; PI-7; PI7; PN-1; Pn1; Serpine2; Spi4
UniProt ID: (Mouse) Q07235
Entrez Gene ID: (Mouse) 20720
multicellular organism development
nervous system development
blood coagulation
negative regulation of cell proliferation
response to wounding
negative regulation of peptidase activity
negative regulation of platelet activation
negative regulation of plasminogen activation
negative regulation of sodium ion transport
negative regulation of endopeptidase activity
negative regulation of protein processing
positive regulation of neuron projection development
negative regulation of phosphatidylinositol 3-kinase signaling
cerebellar granular layer morphogenesis
cell differentiation
negative regulation of blood coagulation
negative regulation of cell growth
secretion by cell
secretory granule organization
negative regulation of protein catabolic process
mating plug formation
negative regulation of proteolysis
negative regulation of smoothened signaling pathway
regulation of timing of cell differentiation
positive regulation of astrocyte differentiation
detection of mechanical stimulus involved in sensory perception
regulation of synaptic transmission, glutamatergic
long-term synaptic potentiation
innervation
seminal vesicle epithelium development
dense core granule biogenesis
negative regulation of platelet aggregation
