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Invitrogen
SET Polyclonal Antibody
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图: 1 / 8
SET Antibody (PA5-115888) in ICC/IF
Immunocytochemistry analysis of SET in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115888) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115888
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SET(Accession Q01105), corresponding to amino acid residues R5-I55.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SET.
靶标信息
SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: chromatin remodelling factor; HLA-DR-associated protein II; I IGAAD; I-2PP2A; I2PP2A; inhibitor of granzyme A-activated DNase; inhibitor-2 of protein phosphatase-2A; leukemogenesis protein; liver regeneration-related protein LRRG026; liver regeneration-related protein LRRGR00002; OTTHUMP00000022286; phosphatase 2A inhibitor I2PP2A; protein phosphatase type 2A inhibitor; RP11-216B9.3; SET; SET nuclear oncogene; SET nuclear proto-oncogene; SET translocation; SET translocation (myeloid leukemia-associated); TAF-1a; TAF-1b; TAF-I; TAF1; I2PP2A; template-activating factor I; Template-Activating Factor-I, chromatin remodelling factor; unnamed protein product
基因别名: 2PP2A; Ab1-115; I2PP2A; IGAAD; IPP2A2; MRD58; PHAPII; Set; TAF-I; TAF-IBETA
UniProt ID: (Human) Q01105, (Rat) Q63945
Entrez Gene ID: (Human) 6418, (Rat) 307947
nucleosome assembly
negative regulation of neuron apoptotic process
endothelial cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
DNA replication
base-excision repair
nucleosome disassembly
granzyme-mediated apoptotic signaling pathway
regulation of transferase activity
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