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Invitrogen
SETDB1 Recombinant Mouse Monoclonal Antibody (H4A4)
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SETDB1 Antibody (MA572130) in WB
Western blot analysis of SETDB1 in HEK-293T lysates (25 µg/lane). Samples were incubated with SETDB1 Recombinant Monoclonal (Product # MA572130) at 1:1,000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA572130
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
H4A4
抗原
Synthetic Peptide.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ERG-associated protein with SET domain; ESET; H3-K9-HMTase 4; Histone H3-K9 methyltransferase 4; Histone-lysine N-methyltransferase SETDB1; Lysine N-methyltransferase 1E; SET domain bifurcated 1; SET domain ERG-associated histone methyltransferase
基因别名: AU022152; ESET; KIAA0067; KMT1E; mKIAA0067; SETDB1
Entrez Gene ID: (Mouse) 84505, (Rat) 689883
negative regulation of transcription from RNA polymerase II promoter
inner cell mass cell proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
methylation
histone lysine methylation
histone H3-K9 trimethylation
bone development
response to vitamin
response to ethanol
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