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Abnova
SF3B2 Monoclonal Antibody (2A2)
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产品信息
H00010992-M10
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2A2
抗原
SF3B2 (AAH07610, 1 a.a. approximately 636 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MDDPSVGPKI PQALEKILQL KESRQEEMNS QQEEEEMETD ARSSLGQSAS ETEEDTVSVS KKEKNRKRRN RKKKKKPQRV RGVSSESSGD REKDSTRSRG SDSPAADVEI EYVTEEPEIY EPNFIFFKRI FEAFKLTDDV KKEKEKEPEK LDKLENSAAP KKKGFEEEHK DSDDDSSDDE QEKKPEAPKL SKKKLRRMNR FTVAELKQLV ARPDVVEMHD VTAQDPKLLV HLKATRNSVP VPRHWCFKRK YLQGKRGIEK PPFELPDFIK RTGIQEMREA LQEKEEQKTM KSKMREKVRP KMGKIDIDYQ KLHDAFFKWQ TKPKLTIHGD LYYEGKEFET RLKEKKPGDL SDELRISLGM PVGPNAHKVP PPWLIAMQRY GPPPSYPNLK IPGLNSPIPE SCSFGYHAGG WGKPPVDETG KPLYGDVFGT NAAEFQTKTE EEEIDRTPWG ELEPSDEESS EEEEEEESDE DKPDETGFIT PADSGLITPG GFSSVPAGME TPELIELRKK KIEEAMDGSE TPQLFTVLPE KRTATVGGAM MGSTHIYDMS TVMSRKGPAP ELQGVEVALA PEELELDPMA MTQKYEEHVR EQQAQVEKED FSDMVAEHAA KQKQKKRKAQ PQDSRGGSKK YKEFKF
靶标信息
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: pre-mRNA splicing factor SF3b 145 kDa subunit; Pre-mRNA-splicing factor SF3b 145 kDa subunit; SAP 145; SF3b145; spliceosome associated protein 145; Spliceosome-associated protein 145; Splicing factor 3B subunit 2; splicing factor 3b, subunit 2, 145kD; splicing factor 3b, subunit 2, 145kDa
基因别名: Cus1; SAP145; SF3b1; SF3B145; SF3b150; SF3B2
UniProt ID: (Human) Q13435
Entrez Gene ID: (Human) 10992
