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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: YEGKEFETRL KEKKPGDLSD ELRISLGMPV GPNAHKVPPP WLIAMQRYGP PPSY
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Pre-mRNA-splicing factor SF3b 145 kDa subunit; SAP 145; SF3b145; Spliceosome-associated protein 145; Splicing factor 3B subunit 2
基因别名: 145kDa; 2610311M13Rik; 2810441F20Rik; B230398H18Rik; SAP145; SF3b1; SF3b145; SF3b150; SF3B2
UniProt ID: (Mouse) Q3UJB0
Entrez Gene ID: (Rat) 293671, (Mouse) 319322