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Bethyl Laboratories
SF3a120/SAP114 Polyclonal Antibody
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FIGURE: 1 / 3
SF3a120/SAP114 Antibody (IHC-00316) in IHC (P)
Detection of human SF3a120/SAP114 by immunohistochemistry. Sample: FFPE section of human pancreatic islet cell tumor. Antibody: Affinity purified rabbit anti-SF3a120/SAP114 (Product # IHC-00316) used at a dilution of 1:250. Detection: DAB.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
IHC-00316
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 300 and 350 of Human splicing factor 3a, subunit 1, 120kDa.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
50 µg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine, Dog, Horse, Rabbit, Panda, Orangutan, Monkey, Gorilla, Northern white-cheeked gibbon, Small-eared galago and Ferret
Target Information
This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SAP 114; SF3a120; Spliceosome-associated protein 114; splicing factor 3 subunit 1; Splicing factor 3A subunit 1
Gene Aliases: 1200014H24Rik; 5930416L09Rik; AI159724; SAP114; SF3A1
UniProt ID: (Mouse) Q8K4Z5
Entrez Gene ID: (Mouse) 67465
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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