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Invitrogen
SFRP2 Polyclonal Antibody
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FIGURE: 1 / 3
SFRP2 Antibody (PA5-106726) in IHC (P)
Immunohistochemistry analysis of SFRP2 in mouse muscle tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with SFRP2 polyclonal antibody (Product # PA5-106726) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-106726
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SFRP2(Accession Q96HF1), corresponding to amino acid residues V119-P169.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total SFRP2.
Target Information
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FRP 2; FRP-2; MGC128911; MGC153618; MGC53344; Protein SDF5; SARP 1; SARP-1; SDF 5; Secreted apoptosis-related protein 1; Secreted frizzled-related protein 2; secreted frizzled-related sequence protein 2; secreted frizzled-related sequence protein 5; sFRP 2; sFRP-2; Sfrp2 protein; stromal cell derived factor 5
Gene Aliases: AI851596; FKSG12; FRP2; SARP1; Sdf5; SFRP2; UNQ361/PRO697
UniProt ID: (Mouse) P97299
Entrez Gene ID: (Rat) 310552, (Mouse) 20319
patterning of blood vessels
somitogenesis
neural tube closure
chondrocyte development
outflow tract morphogenesis
cardiac left ventricle morphogenesis
apoptotic process
signal transduction
response to nutrient
positive regulation of cell proliferation
negative regulation of cell proliferation
male gonad development
anterior/posterior pattern specification
negative regulation of gene expression
negative regulation of cardiac muscle cell apoptotic process
negative regulation of epithelial to mesenchymal transition
positive regulation of endopeptidase activity
neural tube development
regulation of Wnt signaling pathway
negative regulation of Wnt signaling pathway
collagen fibril organization
positive regulation of cell growth
negative regulation of cell growth
negative regulation of cell migration
negative regulation of BMP signaling pathway
cellular response to extracellular stimulus
positive regulation of peptidyl-serine phosphorylation
positive regulation of catenin import into nucleus
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
regulation of cell proliferation
response to drug
negative regulation of mesodermal cell fate specification
embryonic digit morphogenesis
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of JUN kinase activity
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
positive regulation of angiogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
development of primary male sexual characteristics
digestive tract morphogenesis
negative regulation of epithelial cell proliferation
negative regulation of peptidyl-tyrosine phosphorylation
cartilage development
convergent extension involved in axis elongation
bone morphogenesis
sclerotome development
negative regulation of dermatome development
hematopoietic stem cell proliferation
cellular response to X-ray
negative regulation of canonical Wnt signaling pathway
regulation of establishment of planar polarity
planar cell polarity pathway involved in neural tube closure
Wnt signaling pathway involved in somitogenesis
positive regulation of canonical Wnt signaling pathway
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
regulation of stem cell division
negative regulation of planar cell polarity pathway involved in axis elongation
positive regulation of receptor activity
multicellular organism development
Wnt signaling pathway
cell differentiation
canonical Wnt signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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