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Invitrogen
SFTPB Polyclonal Antibody
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产品信息
SA1-72016
产品规格
种属反应
Bovine
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
SP-B purified from Infasurf.
偶联物
形式
Liquid
浓度
20 mg/mL
纯化类型
IgY fraction
保存液
PBS, pH 7.2
内含物
0.075% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
SA1-72016 detects Surfactant Protein B in human, mouse, and rat samples.
SA1-72016 has been successfully used in western blot procedures.
The SA1-72016 immunogen is from Chicken immunized with SP-B purified from Infasurf.
靶标信息
Pulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventilation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B. ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 6 kDa protein; P SFTB3; Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteolipid SPL(Phe); SFPB; SP-B; surfactant, pulmonary-associated protein B
基因别名: SFTP3; SFTPB
UniProt ID: (Bovine) P15781
Entrez Gene ID: (Bovine) 507398
