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Invitrogen
SGEF Polyclonal Antibody
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产品信息
PA5-107064
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N terminal region of human SGEF (aa 1-51).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.4, with 2% sucrose
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Sequence homology: Cow: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 90%
靶标信息
Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Rho guanine nucleotide exchange factor (GEF) 26; Rho guanine nucleotide exchange factor 26; SH3 domain-containing guanine exchange factor; Src homology 3 domain-containing guanine nucleotide exchange factor; testicular tissue protein Li 171
基因别名: ARHGEF26; CSGEF; HMFN1864; SGEF
UniProt ID: (Human) Q96DR7
Entrez Gene ID: (Human) 26084
