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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PEEDLTGLTA SPVPSPTANG LAANNDSPGS GSQSGRKAKD PERGLFPGPQ KSSSEQKLPL QRLPSQENEL LENPSVVLST NSPAALKVGK QQIIPKSLAS EIKISKSNNQ NV
Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 71%.
Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Rho guanine nucleotide exchange factor 26; SH3 domain-containing guanine exchange factor
基因别名: ARHGEF26; HMFN1864; SGEF
Entrez Gene ID: (Human) 26084