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Fabgennix
SGK1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
SGK1-101Y
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 40-90 on human SGK1 protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: serine/threonine protein kinase SGK; Serine/threonine-protein kinase Sgk1; Serum/glucocorticoid-regulated kinase 1
基因别名: SGK; SGK1
Entrez Gene ID: (Rat) 29517
protein phosphorylation
cellular sodium ion homeostasis
apoptotic process
cellular response to DNA damage stimulus
microtubule depolymerization
long-term memory
visual learning
positive regulation of sodium ion transport
peptidyl-serine phosphorylation
positive regulation of cell growth
negative regulation of microtubule polymerization
cellular response to insulin stimulus
regulation of protein localization
negative regulation of apoptotic process
glucocorticoid mediated signaling pathway
neuron projection morphogenesis
positive regulation of dendrite morphogenesis
regulation of cell cycle
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
