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Invitrogen
SGK223 Polyclonal Antibody
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产品信息
PA5-103157
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PRAG1(Accession Q86YV5), corresponding to amino acid residues I1047-H1097.
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Pragmin.
靶标信息
PRAGMIN is also known as SGK223 (sugen kinase 223). The rat homolog was originally identified in a yeast two-hybrid screen for Rnd2 effector proteins expressed in neural cells. Rat Pragmin was found to stimulate RhoA activity for the regulation of neurite outgrowth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homolog of rat pragma of Rnd2; Inactive tyrosine-protein kinase PRAG1; Notch activation complex kinase; PEAK family member 2; PEAK1-related kinase-activating pseudokinase 1; Pragma of Rnd2; Pragmin; Pragmin, RND2 effector protein; SgK223; Sugen kinase 223; tyrosine-protein kinase PRAG1; Tyrosine-protein kinase SgK223
基因别名: 9830148H23; D8Ertd82e; mFLJ00269; NACK; PEAK2; PRAG1; PRAGMIN; RGD1311793; SGK223
UniProt ID: (Mouse) Q571I4, (Human) Q86YV5, (Rat) D3ZMK9
Entrez Gene ID: (Mouse) 244418, (Human) 157285, (Rat) 306506
nucleotide binding
molecular_function
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein binding
identical protein binding
non-receptor serine/threonine protein kinase
protein modifying enzyme
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