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Invitrogen
SGSM1 Polyclonal Antibody
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产品信息
PA5-52038
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SPDSGHPSSH NFSSGLSEHS EPSLSTEDSV LDAQRNTPTV LRPRDGSVDD RQSSEATTSQ DEAPREELAV QDSLESDLLA NESMDEFMSI TGSLDMALPE KDDVVMEGWR SSETEKHGQA DSEDNLSEEP EMESLFPALA SLAVTT
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.
靶标信息
Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1, 148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.
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生物信息学
蛋白别名: RUN and TBC1 domain containing 2; RUN and TBC1 domain-containing protein 2; Small G protein signaling modulator 1; small G protein signaling modulator 1 protein
基因别名: KIAA1941; RUTBC2; SGSM1
UniProt ID: (Human) Q2NKQ1
Entrez Gene ID: (Human) 129049
