Anti-SGSM2 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the internal region of human SGSM2.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: RUN and TBC1 domain containing 1; RUN and TBC1 domain-containing protein 1; Small G protein signaling modulator 2; small G protein signaling modulator 2 protein

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基因别名: D630003G22Rik; KIAA0397; mKIAA0397; R74628; RUTBC1; SGSM2

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UniProt ID: (Human) O43147, (Mouse) Q80U12

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Entrez Gene ID: (Human) 9905, (Rat) 303304, (Mouse) 97761

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功能

GTPase activator activity Rab GTPase binding GTPase-activating protein

参与通路

intracellular protein transport regulation of vesicle fusion late endosome to Golgi transport positive regulation of GTPase activity activation of GTPase activity