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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: ENLSNLRYLM KFLARLAEEQ EVNKMTPSNI AIVLGPNLLW PPEKEGDQAQ LDAASVSSIQ VVGVVEALIQ SADTLFPGDI NFNVSGLFSA VTLQDTVSDR LASEELPSTA VPTPATTPAP APAPAPAPAP ALASAATKER TESEVPP
Highest antigen sequence indentity to the following orthologs: Rat - 74%, Mouse - 75%.
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.
仅用于科研。不用于诊断过程。未经明确授权不得转售。