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Invitrogen
SH3BP1 Monoclonal Antibody (OTI2F4)
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SH3BP1 Antibody (MA5-27469) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded human lymphoma tissue. To expose target proteins, heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min. Following antigen retrieval, tissues were probed with a SH3BP1 monoclonal antibody (Product # MA5-27469) at a dilution of 1:500.
产品信息
MA5-27469
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI2F4
抗原
Full length human recombinant protein of SH3BP1 produced in HEK293T cell
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3BP-1; OTTHUMP00000028981; SH3 domain-binding protein 1; SH3-domain binding protein 1
基因别名: ARHGAP43; SH3BP1
UniProt ID: (Human) Q9Y3L3
Entrez Gene ID: (Human) 23616
