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Invitrogen
SH3KBP1 Polyclonal Antibody
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SH3KBP1 Antibody (PA5-96007) in WB
Western blot analysis of SH3KBP1 in extracts of THP-1 cells. Samples were incubated with SH3KBP1 Polyclonal antibody (Product # PA5-96007) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-96007
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 136-271 of human SH3KBP1 (NP_1140981)
偶联物
形式
Liquid
浓度
2.54 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: WEGVLNGKTG MFPSNFIKEL SGESDELGIS QDEQLSKSSL RETTGSESDG GDSSSTKSEG ANGTVATAAI QPKKVKGVGF GDIFKDKPIK LRPRSIEVEN DFLPVEKTIG KKLPATTATP DSSKTEMDSR TKSKDY; Positive Samples: THP-1; Cellular Location: Cell junction, Cytoplasm, Cytoplasmic vesicle membrane, Peripheral membrane protein, cytoskeleton, focal adhesion, synapse, synaptosome
靶标信息
This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: c-Cbl-interacting protein; Cbl-interacting protein of 85 kDa; CD2-binding protein 3; CD2BP3; HSB-1; Human Src family kinase-binding protein 1; migration-inducing gene 18; Regulator of ubiquitous kinase; Ruk; SH3 domain-containing kinase-binding protein 1; SH3-containing, expressed in tumorigenic astrocytes; SH3-domain kinase binding protein 1; Src family kinase-binding protein 1; src-related kinase binding protein-1
基因别名: 1200007H22Rik; 1700125L08Rik; 5830464D22Rik; AI447724; CD2BP3; CIN85; GIG10; HSB-1; HSB1; IN85; MIG18; Ruk; Seta; SH3KBP1
UniProt ID: (Human) Q96B97, (Mouse) B1AZ86
Entrez Gene ID: (Human) 30011, (Mouse) 58194
