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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: ASRPNFLAPL PHEVTQLRLG EAAALENNTG SEATGPSRPL PDAPHGVMDS GLPWSKDWKG SKDVLRKASS DMSASAGYEE ISDPDMEEKP SLPPRKESII KS
Antigen sequence identity: Mouse 82%; Rat 83%
Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adapter protein HOFI; Factor for adipocyte differentiation 49; FLJ20831; SH3 and PX domain-containing protein 2B; Tyrosine kinase substrate with four SH3 domains
基因别名: FAD49; KIAA1295; SH3PXD2B; TKS4
Entrez Gene ID: (Human) 285590