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Invitrogen
SH3PXD2B Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-57673
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PPGVILPMMP AKHIPPARDS RRPEPKPDKS RLFQLKNDMG LECGHKVLAK EVKKPNLRPI SKSKTDLPEE KPDATPQNPF LKSRPQV
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 80%.
靶标信息
Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: adapter protein HOFI; adaptor protein HOFI; factor for adipocyte differentiation 49; FLJ20831; homolog of FISH; tyrosine kinase substrate with four SH3 domains; unnamed protein product
基因别名: FAD49; FTHS; HOFI; KIAA1295; TKS4; TSK4
UniProt ID: (Human) A1X283
Entrez Gene ID: (Human) 285590
skeletal system development
eye development
osteoblast fate commitment
superoxide metabolic process
heart development
positive regulation of gene expression
extracellular matrix disassembly
positive regulation of multicellular organism growth
superoxide anion generation
positive regulation of fat cell differentiation
skeletal system morphogenesis
positive regulation of stress fiber assembly
bone development
regulation of brood size
adipose tissue development
podosome assembly
protein localization to membrane
positive regulation of adipose tissue development
cranial skeletal system development
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