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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: AVTNASQAKV PMSTAGQTSR GVTMVSPSTA GGPAQKLQGN GVAGSPSVVP AAVVSAAHIQ TSPQAKVLLH
Highest antigen sequence indentity to the following orthologs: Mouse - 91%, Rat - 94%.
This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase SH3RF1; FLJ21602; Plenty of SH3s; Protein POSH; RING finger protein 142; RING-type E3 ubiquitin transferase SH3RF1; SH3 domain-containing RING finger protein 1; SH3 multiple domains protein 2
基因别名: KIAA1494; POSH; POSH1; RNF142; SH3MD2; SH3RF1
Entrez Gene ID: (Human) 57630